Reference videos reduce variability of motor dysfunction assessments in multiple sclerosis

D'Souza, M.; Steinheimer, Saskia Marie; Dorn, J.; Morrison, C.; Boisvert, J.; Kravalis, K.; Burggraaff, J.; van Munster, C. E.; Diederich, M.; Sellen, A.; Kamm, Christian Philipp; Dahlke, F.; Uitdehaag, B. M.; Kappos, L. (2018). Reference videos reduce variability of motor dysfunction assessments in multiple sclerosis. Multiple sclerosis journal - experimental, translational and clinical, 4(3), p. 2055217318792399. Sage Publications 10.1177/2055217318792399

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Motor dysfunction, particularly ataxia, is one of the predominant clinical manifestations in patients with multiple sclerosis (MS). Assessment of motor dysfunction suffers from a high variability. We investigated whether the clinical rating of ataxia can be improved through the use of reference videos, covering the spectrum of severity degrees as defined in the Neurostatus-Expanded Disability Status Scale. Twenty-five neurologists participated. The variability of their assessments was significantly lower when reference videos were used (SD = 0.12; range = 0.40 vs SD = 0.26; range = 0.88 without reference videos; p = 0.013). Reference videos reduced the variability of clinical assessments and may be useful tools to improve the precision and consistency in the clinical assessment of motor functions in MS.

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