Sequential morphometric evaluation at UnicCa and DCD implant surfaces. An experimental study in the dog.

Favero, Vittorio; Lang, Niklaus Peter; Favero, Riccardo; Antunes, Antonio A; Salata, Luiz A; Botticelli, Daniele (2017). Sequential morphometric evaluation at UnicCa and DCD implant surfaces. An experimental study in the dog. Clinical oral implants research, 28(7), pp. 833-839. Wiley-Blackwell 10.1111/clr.12888

Text Favero_et_al-2017-Clinical_Oral_Implants_Research.pdf - Published Version Restricted to registered users only Available under License Publisher holds Copyright. Download (2MB)

AIM

To study tissue components adjacent to implants with nanotechnologically modified surfaces at different periods of healing.

MATERIAL & METHODS

In 12 beagle dogs, two different implant systems with different surface configurations were randomly installed in the edentulous premolar regions of the mandible. One surface was first acid-etched and subsequently, nanotechnologically modified with calcium ions (UnicCa ), while the other was first sandblasted and acid-etched, and then additionally treated with a nanometer calcium phosphate deposition (discrete crystalline deposition; DCD ). The implants were fully submerged; surgeries and sacrifices were planned to harvest biopsies after 1, 2, 4 and 8 weeks of healing (n = 6 per period). A morphometric evaluation of percentages of new and old bone, bone debris/particles and clot, new soft tissues (provisional matrix and immature marrow), mature bone marrow and vessels was performed in the spongiosa compartment adjacent to the implant surface up to a distance of about 0.4 mm from the surface.

RESULTS

After 2 weeks of healing, the soft tissues were represented by 41.0% at the UnicCa and 37.9% at the DCD surfaces, in both cases mainly being composed of provisional matrix. These percentages decreased over time, being composed of greater amounts of immature bone marrow, and disappeared after 8 weeks. New bone increased progressively between 1 and 8 weeks of healing from 9.7 ± 6.3% to 70.0 ± 8.4% and from 8.2 ± 3.5% to 67.0 ± 6.1% at the UnicCa and DCD surfaces, respectively. Pristine bone was progressively resorbed.

CONCLUSIONS

Throughout the periods of healing observed, the formation of a provisional matrix followed by the formation of new bone and marrow was revealed in a similar fashion as for other modified surface configurations.

Interest & Impact

Downloads

1 since deposited on 26 Jul 2019
0 in the past 12 months

Citations

5 Citations in Web of Science ®
6 Citations in Scopus

Search

in Google Scholar™

Services

Actions (login required)

Edit item

Actions (login required)

Edit item