Sevoflurane remifentanil interaction: comparison of different response surface models

Heyse, Bjorn; Proost, Johannes H; Schumacher, Peter M; Bouillon, Thomas W; Vereecke, Hugo E M; Eleveld, Douglas J; Luginbühl, Martin; Struys, Michel M R F (2012). Sevoflurane remifentanil interaction: comparison of different response surface models. Anesthesiology, 116(2), pp. 311-23. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/ALN.0b013e318242a2ec

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Various pharmacodynamic response surface models have been developed to quantitatively describe the relationship between two or more drug concentrations with their combined clinical effect. We examined the interaction of remifentanil and sevoflurane on the probability of tolerance to shake and shout, tetanic stimulation, laryngeal mask airway insertion, and laryngoscopy in patients to compare the performance of five different response surface models.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic and Policlinic for Anaesthesiology and Pain Therapy

UniBE Contributor:

Luginbühl, Martin

ISSN:

0003-3022

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Jeannie Wurz

Date Deposited:

04 Oct 2013 14:33

Last Modified:

05 Dec 2022 14:10

Publisher DOI:

10.1097/ALN.0b013e318242a2ec

PubMed ID:

22222473

Web of Science ID:

000299666200011

URI:

https://boris.unibe.ch/id/eprint/13009 (FactScience: 219510)

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