cTBS over contralesional homologue areas deteriorates speech output in isolated apraxia of speech after stroke

Kaufmann, Brigitte C.; Pastore-Wapp, Manuela; Lübeck, Maria; Koenig, Monica; Bohlhalter, Stephan; Vanbellingen, Tim; Cazzoli, Dario; Nyffeler, Thomas (2019). cTBS over contralesional homologue areas deteriorates speech output in isolated apraxia of speech after stroke. Brain stimulation, 12(4), pp. 1069-1071. Elsevier 10.1016/j.brs.2019.03.024

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Apraxia of speech (AOS) is an impairment of motor speech planning/programming, characterized by a combination of phonemic segmental changes and articulatory distortions [1]. AOS is most often accompanied by aphasia, whereas isolated forms may rarely occur after focal damage to the left precentral gyrus [1]. How AOS recovers after brain damage is poorly understood [2]. In particular, it is not known whether recovery of AOS solely depends on the functional reorganisation of perilesional areas [3,4], or whether it also depends on the compensation through contralesional homologue areas.

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