Multifocal Vasculopathy Due to Varicella‐Zoster Virus (VZV): Serial Analysis of VZV DNA and Intrathecal Synthesis of VZV Antibody in Cerebrospinal Fluid

Kronenberg, Andreas; Schupbach, Reto; Schuknecht, Bernhard; Bossart, Walter; Weber, Rainer; Gilden, Donald H.; Speck, Roberto F. (2002). Multifocal Vasculopathy Due to Varicella‐Zoster Virus (VZV): Serial Analysis of VZV DNA and Intrathecal Synthesis of VZV Antibody in Cerebrospinal Fluid. Clinical infectious diseases, 35(3), pp. 330-333. The University of Chicago Press 10.1086/341492

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Recognition of multifocal vasculopathy due to varicella-zoster virus (VZV) is often problematic. We describe a human immunodeficiency virus-infected patient who had progressive central nervous system disease for >3 months. Both VZV DNA and antibody were detected in cerebrospinal fluid (CSF) specimens; serial polymerase chain reaction analyses confirmed the diagnosis and guided the duration of therapy. Reduced ratios of VZV antibody in serum to that in CSF were also demonstrated.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology

UniBE Contributor:

Kronenberg, Andreas Oskar

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1058-4838

Publisher:

The University of Chicago Press

Language:

English

Submitter:

Andreas Oskar Kronenberg

Date Deposited:

03 Feb 2021 10:38

Last Modified:

05 Dec 2022 15:36

Publisher DOI:

10.1086/341492

PubMed ID:

12115101

BORIS DOI:

10.48350/139175

URI:

https://boris.unibe.ch/id/eprint/139175

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