Schuerch, Kaspar; Ma, Jeffrey H; Wolf, Sebastian; Ebneter, Andreas; Zinkernagel, Martin S.; Munk, Marion R. (2021). Longitudinal Retinal Layer Changes and Clinical Outcome in Patients with Multiple Evanescent White Dot Syndrome. Ocular immunology and inflammation, 29(6), pp. 1114-1120. Taylor & Francis 10.1080/09273948.2020.1717545
Full text not available from this repository. (Request a copy)Purpose: To evaluate longitudinal changes in retinal layer thickness and clinical outcome in patients with MEWDS.Methods: In 20 patients with MEWDS, SD-OCT images and BCVA were assessed at baseline, and at months 1, 3, and 12. SD-OCTs were segmented and measurements were performed within the fovea and a MEWDS lesion. Baseline and follow-up values in the affected eye were compared to measurements performed at the corresponding location in the fellow eye.Results: ONL thickness was 4.7% thicker in MEWDS-eyes compared with the baseline, with a significant decrease of 9% at 3 months. Within the lesion, INL thickness was 7.9% increased at baseline and decreased significantly over the follow-up of 12 months. BCVA was decreased at baseline (0.2 ± 0.18logMAR) and at the 3 months but after 12 months had increased to 0.01 ± 0.04 logMAR.Conclusion: MEWDS shows the involvement of different retinal layers and characteristic changes over the disease course.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology |
UniBE Contributor: |
Schürch, Kaspar Werner, Wolf, Sebastian (B), Ebneter, Andreas, Zinkernagel, Martin Sebastian, Munk, Marion |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1744-5078 |
Publisher: |
Taylor & Francis |
Language: |
English |
Submitter: |
Marion Munk |
Date Deposited: |
06 Apr 2020 17:53 |
Last Modified: |
02 Mar 2023 23:33 |
Publisher DOI: |
10.1080/09273948.2020.1717545 |
PubMed ID: |
32125930 |
Uncontrolled Keywords: |
MEWDS Multiple evanescent white dot syndrome ganglion cells optical coherence tomography photoreceptors |
URI: |
https://boris.unibe.ch/id/eprint/141986 |
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