Krasniqi, Nazmi; Segalada, Diana; Lüscher, Thomas F; Lippuner, Kurt; Haegeli, Laurent; Steffel, Jan; Wolber, Thomas; Brunckhorst, Corinna; Holzmeister, Johannes; Hürlimann, David; Duru, Firat (2012). Falls and fractures in the elderly with sinus node disease: the impact of pacemaker implantation. Cardiology research and practice, 2012, p. 498102. Cairo (Egypt): SAGE Hindawi 10.1155/2012/498102
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Background. Falls and fractures in the elderly are among the leading causes of disability. We investigated whether pacemaker implantation prevents falls in patients with SND in a large cohort of patients. Methods. Patient demographics and medical history were collected prospectively. Fall history was retrospectively reconstituted from available medical records. The 10-year probability for major osteoporotic fractures was calculated retrospectively from available medical records using the Swiss fracture risk assessment tool FRAX-Switzerland. Results. During a mean observation period of 2.3 years after implantation, the rates of fallers and injured fallers with fracture were reduced to 15% and 6%, respectively. This corresponds to a relative reduction in the number of fallers of 75% (P < 0.001) and of injured fallers of 63% (P = 0.014) after pacemaker implantation. Similarly, the number of falls was reduced from 60 (48%) before pacemaker implantation to 22 (18%) thereafter (relative reduction 63%, P = 0.035) and the number of falls with injury from 22 (18%) to 7 (6%), which corresponds to a relative reduction of 67%, P = 0.013. Conclusion. In patients with SND, pacemaker implantation significantly reduces the number of patients experiencing falls, the total number of falls, and the risk for osteoporotic fractures.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Orthopaedic, Plastic and Hand Surgery (DOPH) > Clinic of Osteoporosis |
UniBE Contributor: |
Lippuner, Kurt |
ISSN: |
2090-8016 |
Publisher: |
SAGE Hindawi |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:35 |
Last Modified: |
05 Dec 2022 14:11 |
Publisher DOI: |
10.1155/2012/498102 |
PubMed ID: |
23150844 |
BORIS DOI: |
10.7892/boris.14201 |
URI: |
https://boris.unibe.ch/id/eprint/14201 (FactScience: 221056) |