Maharjan, Niran; Saxena, Smita (2020). It Takes Two to Tango: DPRs in ALS and SCA36. Neuron, 107(2), pp. 202-204. Cell Press 10.1016/j.neuron.2020.06.025
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Dipeptide repeat proteins (DPRs) occur via repeat-associated non-AUG (RAN) translation. In this issue of Neuron, McEachin et al. (2020) show that the aggregation-prone poly(GA)-rich chimeric DPRs determine divergent poly(GP) mediated pathology between C9ALS/FTD and SCA36.
Item Type: |
Journal Article (Further Contribution) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DCR Unit Sahli Building > Forschungsgruppe Neurologie 04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology |
UniBE Contributor: |
Maharjan, Niran, Saxena, Smita |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0896-6273 |
Publisher: |
Cell Press |
Language: |
English |
Submitter: |
Chantal Kottler |
Date Deposited: |
13 Nov 2020 14:38 |
Last Modified: |
05 Dec 2022 15:41 |
Publisher DOI: |
10.1016/j.neuron.2020.06.025 |
PubMed ID: |
32702342 |
BORIS DOI: |
10.7892/boris.147714 |
URI: |
https://boris.unibe.ch/id/eprint/147714 |
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