Müller, Stefan; Schaffer, Thomas; Flogerzi, Beatrice; Seibold-Schmid, Beatrice; Schnider, Jasmin; Takahashi, Kazue; Darfeuille-Michaud, Arlette; Vazeille, Emilie; Schoepfer, Alain M; Seibold, Frank (2010). Mannan-binding lectin deficiency results in unusual antibody production and excessive experimental colitis in response to mannose-expressing mild gut pathogens. Gut, 59(11), pp. 1493-500. London: BMJ Publishing Group 10.1136/gut.2010.208348
Full text not available from this repository.In Crohn's disease (CD) the deficiency of mannan-binding lectin (MBL) is associated with an increased prevalence of anti-Saccharomyces cerevisiae antibodies (ASCA) and with complicated phenotypes of the disease. However, the role of MBL in intestinal inflammation is currently unclear. A study was undertaken to analyse local MBL expression in human intestine and the consequences of MBL deficiency in experimental colitis and yeast infection.
Item Type: |
Journal Article (Original Article) |
---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Gastroenterology |
UniBE Contributor: |
Seibold, Frank Werner |
ISSN: |
0017-5749 |
Publisher: |
BMJ Publishing Group |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:10 |
Last Modified: |
05 Dec 2022 14:01 |
Publisher DOI: |
10.1136/gut.2010.208348 |
PubMed ID: |
20682699 |
Web of Science ID: |
000282963100012 |
URI: |
https://boris.unibe.ch/id/eprint/1490 (FactScience: 203173) |