Frase, Lukas; Jahn, Friederike; Tsodor, Sulamith; Krone, Lukas; Selhausen, Peter; Feige, Bernd; Maier, Jonathan G.; Piosczyk, Hannah; Riemann, Dieter; Nitsche, Michael A.; Nissen, Christoph (2021). Offline Bi‐Frontal Anodal Transcranial Direct Current Stimulation Decreases Total Sleep Time Without Disturbing Overnight Memory Consolidation. Neuromodulation, 24(5), pp. 910-915. Wiley 10.1111/ner.13163
|
Text
ner.13163.pdf - Published Version Available under License Creative Commons: Attribution-Noncommercial-No Derivative Works (CC-BY-NC-ND). Download (197kB) | Preview |
Objectives: A proposed replay of memory traces between the hippocampus and frontal cortical brain areas during sleep is of high relevance for overnight memory consolidation. Recently, we demonstrated that bi-frontal anodal transcranial direct current stimulation (tDCS) prior to sleep increases waking EEG gamma power and decreases total sleep time during the night. It is unclear whether this effect on cortical excitability has an influence on overnight memory consolidation. We hypothesized that bi-frontal evening tDCS interferes with overnight memory consolidation with a polarity specific impairment following anodal tDCS.
Materials and methods: Nineteen healthy participants underwent a within-subject, repeated-measures protocol in the sleep laboratory with bi-frontal tDCS applied prior to sleep according to the experimental protocol (anodal, cathodal, sham stimulation). Memory tasks for declarative and procedural memory were assessed prior to tDCS and on the following morning.
Results: No deterioration of overnight memory consolidation following evening offline bi-frontal tDCS could be detected.
Conclusion(s): The application of tDCS can be considered safe regarding overnight memory consolidation and represents a promising treatment approach in conditions of decreased vigilance and arousal.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Translational Research Center 04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy |
UniBE Contributor: |
Maier, Jonathan Gabriel, Nissen, Christoph |
Subjects: |
100 Philosophy > 150 Psychology 600 Technology > 610 Medicine & health |
ISSN: |
1525-1403 |
Publisher: |
Wiley |
Language: |
English |
Submitter: |
Ersilia Trinca |
Date Deposited: |
05 Jan 2021 16:52 |
Last Modified: |
05 Dec 2022 15:43 |
Publisher DOI: |
10.1111/ner.13163 |
PubMed ID: |
32394544 |
BORIS DOI: |
10.48350/150185 |
URI: |
https://boris.unibe.ch/id/eprint/150185 |
Actions (login required)
 |
Edit item |