Severe Autoimmune Diseases

Henes, Melanie; von Wolff, Michael; Henes, Joerg (2020). Severe Autoimmune Diseases. In: von Wolff, Michael; Nawroth, Frank (eds.) Fertility Preservation in Oncological and Non-Oncological Diseases (pp. 123-131). Cham: Springer 10.1007/978-3-030-47568-0_15

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This section deals with ovarian protection in non-malignant, rheumatic or other autoimmune diseases. Since these diseases are disproportionately common in young women, knowledge of the negative effects of immunosuppressive agents on the ovarian reserve, as well as the possibilities and limitations of ovarian protective measures, even in this particular patient population, is essential. According to current data, we should offer patients at increased risk of POI treatment with GnRH analogues when using cyclophosphamide. In addition, the use of ovarian cryopreservation (short time frame, sufficiently high ovarian reserve) should be generously considered. Ovarian stimulation therapy is only advisable in rare cases, as many patients are at risk of exacerbation of the underlying disease.

Item Type:

Book Section (Book Chapter)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Gynaecology

UniBE Contributor:

von Wolff, Michael

Subjects:

600 Technology > 610 Medicine & health

ISBN:

978-3-030-47567-3

Publisher:

Springer

Language:

English

Submitter:

Monika Zehr

Date Deposited:

16 Mar 2021 14:28

Last Modified:

05 Dec 2022 15:49

Publisher DOI:

10.1007/978-3-030-47568-0_15

BORIS DOI:

10.48350/153978

URI:

https://boris.unibe.ch/id/eprint/153978

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