Hoenemann, Christian; Ostendorf, Norbert; Zarbock, Alexander; Doll, Dietrich; Hagemann, Olaf; Zimmermann, Mathias; Luedi, Markus (2021). Reticulocyte and Erythrocyte Hemoglobin Parameters for Iron Deficiency and Anemia Diagnostics in Patient Blood Management. A Narrative Review. Journal of clinical medicine, 10(18) MDPI 10.3390/jcm10184250
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Anemia, iron deficiency and other hematinic deficiencies are a major cause of perioperative transfusion needs and are associated with increased morbidity and mortality. Anemia can be caused either by decreased production of hemoglobin or red blood cells or by increased consumption and blood loss. Decreased production can involve anything from erythropoietin or vitamin B12 insufficiency to absolute or functional lack of iron. Thus, to achieve the goal of patient blood management, anemia must be addressed by addressing its causes. The traditional parameters to diagnose anemia, despite offering elaborate options, are not ideally suited to giving a simple overview of the causes of anemia, e.g., iron status for erythropoiesis, especially during the acute phase of inflammation, acute blood loss or iron deficiency. Reticulocyte hemoglobin can thus help to uncover the cause of the anemia and to identify the main factors inhibiting erythropoiesis. Regardless of the cause of anemia, reticulocyte hemoglobin can also quickly track the success of therapy and, together with the regular full blood count it is measured alongside, help in clearing the patient for surgery.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic and Policlinic for Anaesthesiology and Pain Therapy |
UniBE Contributor: |
Lüdi, Markus |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
2077-0383 |
Publisher: |
MDPI |
Language: |
English |
Submitter: |
Jeannie Wurz |
Date Deposited: |
15 Oct 2021 09:17 |
Last Modified: |
28 Sep 2023 19:07 |
Publisher DOI: |
10.3390/jcm10184250 |
PubMed ID: |
34575361 |
Uncontrolled Keywords: |
anemia, anemia of inflammation, anemia of chronic disease (ACD), hospital-acquired anemia, iron deficiency, patient blood management reticulocyte hemoglobin (Ret He) |
BORIS DOI: |
10.48350/159727 |
URI: |
https://boris.unibe.ch/id/eprint/159727 |
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