NMR relaxation time investigation of highly diluted aqueous solutions of silica-lactose

Esposito, Fernando; Wolf, Ursula; Baumgartner, Stephan (2021). NMR relaxation time investigation of highly diluted aqueous solutions of silica-lactose. Journal of molecular liquids, 337(115975), p. 115975. Elsevier Science B.V. 10.1016/j.molliq.2021.115975

[img] Text
Esposito2021.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (717kB) | Request a copy
[img]
Preview
Text
Esposito2021PostPrint.pdf - Accepted Version
Available under License Creative Commons: Attribution-Noncommercial-No Derivative Works (CC-BY-NC-ND).

Download (1MB) | Preview

The aim of the present investigation was to replicate a study published by Demangeat in 2010 in the Journal of Molecular Liquids. We measured 20 MHz longitudinal (T1) and transverse (T2) proton relaxation of H2O in highly diluted silica-lactose (Sil/Lac) solutions in 0.15 M LiCl in water (Sil/Lac C6–C24, range 10 -7 M–10 -47 M). The samples were prepared by repetitive succussion and centesimal dilution under rigorously controlled laboratory conditions. Lactose solutions in 0.15 M LiCl in water (Lac C6–C24) were identically and simultaneously treated, as controls. Neither for lactose (Lac) nor for Sil/Lac solutions did T1 and T2 relaxation parameters show a significant correlation with increasing dilution level. A cross-correlation analysis of T1 and T2 revealed a significant negative correlation for both Sil/Lac and LiCl samples, which changed to positive after placing the tubes for 10 min in boiling water. These results diverge from those obtained in the study of Demangeat. In our investigation, the process of potentisation (repetitive succussion and dilution) seems to be responsible for the modifications of proton relaxation times, irrespective of the presence of silica. We hypothesise that succussion intensity during dilution is a crucial factor that needs to be investigated in more detail in future investigations.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Medical Education > Institute of Complementary and Integrative Medicine (IKIM)

UniBE Contributor:

Wolf, Ursula, Baumgartner, Stephan

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0167-7322

Publisher:

Elsevier Science B.V.

Language:

English

Submitter:

Maurice Gisler

Date Deposited:

17 Nov 2021 11:33

Last Modified:

30 Apr 2023 00:25

Publisher DOI:

10.1016/j.molliq.2021.115975

BORIS DOI:

10.48350/160616

URI:

https://boris.unibe.ch/id/eprint/160616

Actions (login required)

Edit item Edit item
Provide Feedback