Clinicopathologic features and long-term outcomes of NUT midline carcinoma

Bauer, Daniel E; Mitchell, Chelsey M; Strait, Kelly M; Lathan, Christopher S; Stelow, Edward B; Lüer, Sonja C; Muhammed, Somala; Evans, Andrew G; Sholl, Lynette M; Rosai, Juan; Giraldi, Eugenia; Oakley, Richard P; Rodriguez-Galindo, Carlos; London, Wendy B; Sallan, Stephen E; Bradner, James E; French, Christopher A (2012). Clinicopathologic features and long-term outcomes of NUT midline carcinoma. Clinical cancer research, 18(20), pp. 5773-9. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-12-1153

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NUT midline carcinoma (NMC) is a poorly differentiated squamous cancer characterized by rearrangement of the NUT gene. Research advances have provided opportunities for targeted therapy in NMC, yet the clinical features of this rare disease have not been systematically characterized. We report on a large population of such patients to identify the disease characteristics and treatments, correlate them with outcome, and to consider clinical recommendations.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine

UniBE Contributor:

Lüer, Sonja

ISSN:

1078-0432

Publisher:

American Association for Cancer Research

Language:

English

Submitter:

Anette van Dorland

Date Deposited:

04 Oct 2013 14:41

Last Modified:

02 Mar 2023 23:21

Publisher DOI:

10.1158/1078-0432.CCR-12-1153

PubMed ID:

22896655

Web of Science ID:

000311908500028

URI:

https://boris.unibe.ch/id/eprint/16548 (FactScience: 224203)

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