Contente, Martina L.; Marzuoli, Irene; Iding, Hans; Wetzl, Dennis; Puentener, Kurt; Hanlon, Steven P.; Paradisi, Francesca (2022). Screening methods for enzyme-mediated alcohol oxidation. Scientific reports, 12(1), p. 3019. Springer Nature 10.1038/s41598-022-07008-7
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Alcohol oxidation for the generation of carbonyl groups, is an essential reaction for the preparation
of fine chemicals. Although a number of chemical procedures have been reported, biocatalysis is a promising alternative for more sustainable and selective processes. To speed up the discovery of novel (bio)catalysts for industrial applications, efficient screening approaches need to be established. Here, we report on an enzyme‐mediated alcohol oxidation screening platform to rapidly detect the activities and selectivities of three classes of biocatalysts; ketoreductases (KREDs), alcohol oxidases (AlcOXs) and laccase‐mediator systems (LMSs) with diverse substrates.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP) |
UniBE Contributor: |
Contente, Martina Letizia, Paradisi, Francesca |
Subjects: |
500 Science > 540 Chemistry |
ISSN: |
2045-2322 |
Publisher: |
Springer Nature |
Funders: |
[UNSPECIFIED] F. Hoffmann-La Roche |
Language: |
English |
Submitter: |
Francesca Paradisi |
Date Deposited: |
23 Feb 2022 16:39 |
Last Modified: |
05 Dec 2022 16:10 |
Publisher DOI: |
10.1038/s41598-022-07008-7 |
PubMed ID: |
35194101 |
BORIS DOI: |
10.48350/165920 |
URI: |
https://boris.unibe.ch/id/eprint/165920 |
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