Catheter Ablation of Atrial Fibrillation in Patients with Previous Lobectomy or Partial Lung Resection: Long-Term Results of an International Multicenter Study.

Demarchi, Andrea; Conte, Giulio; Chen, Shih-Ann; Lo, Li-Wei; Chen, Wei-Tso; De Potter, Tom; Geelen, Peter; Sarkozy, Andrea; Spera, Francesco R; Reichlin, Tobias; Roten, Laurent; Defaye, Pascal; Carabelli, Adrien; Boveda, Serge; Bourenane, Hamed; Riesinger, Lisa; Kochhäuser, Simon; Caixal, Gala; Mont, Lluis; Scherr, Daniel; ... (2022). Catheter Ablation of Atrial Fibrillation in Patients with Previous Lobectomy or Partial Lung Resection: Long-Term Results of an International Multicenter Study. Journal of clinical medicine, 11(6) MDPI 10.3390/jcm11061481

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INTRODUCTION

Data regarding the efficacy of catheter ablation in patients with atrial fibrillation (AF) and patients' previous history of pulmonary lobectomy/pneumonectomy are scanty. We sought to evaluate the efficacy and long-term follow-up of catheter ablation in this highly selected group of patients.

MATERIAL AND METHODS

Twenty consecutive patients (8 females, 40%; median age 65.2 years old) with a history of pneumonectomy/lobectomy and paroxysmal or persistent AF, treated by means of pulmonary vein isolation (PVI) at ten participating centers were included. Procedural success, intra-procedural complications, and AF recurrences were considered.

RESULTS

Fifteen patients had a previous lobectomy and five patients had a complete pneumonectomy. A large proportion (65%) of PV stumps were electrically active and represented a source of firing in 20% of cases. PVI was performed by radiofrequency ablation in 13 patients (65%) and by cryoablation in the remaining 7 cases. Over a median follow up of 29.7 months, a total of 7 (33%) AF recurrences were recorded with neither a difference between patients treated with cryoablation or radiofrequency ablation or between the two genders.

CONCLUSIONS

Catheter ablation by radiofrequency ablation or cryoablation in patients with pulmonary stumps is feasible and safe. Long-term outcomes are favorable, and a similar efficacy of catheter ablation has been noticed in both males and females.

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