Urbano, Valentina; Novy, Jan; Alvarez, Vincent; Schindler, Kaspar; Rüegg, Stephan; Rossetti, Andrea O (2022). EEG recording latency in critically ill patients: Impact on outcome. An analysis of a randomized controlled trial (CERTA). Clinical neurophysiology, 139, pp. 23-27. Elsevier 10.1016/j.clinph.2022.04.003
|
Text
1-s2.0-S1388245722002346-main.pdf - Published Version Available under License Creative Commons: Attribution-Noncommercial-No Derivative Works (CC-BY-NC-ND). Download (276kB) | Preview |
OBJECTIVE
To assess, in adults with acute consciousness impairment, the impact of latency between hospital admission and EEG recording start, and their outcome.
METHODS
We reviewed data of the CERTA trial (NCT03129438) and explored correlations between EEG recording latency and mortality, Cerebral Performance Categories (CPC), and modified Rankin Scale (mRS) at 6 months, considering other variables, using uni- and multivariable analyses.
RESULTS
In univariable analysis of 364 adults, median latency between admission and EEG recordings was comparable between surviving (61.1 h; IQR: 24.3-137.7) and deceased patients (57.5 h; IQR: 22.3-141.1); p = 0.727. This did not change after adjusting for potential confounders, such as lower Glasgow Coma Score on enrolment (p < 0.001) and seizure or status epilepticus detection (p < 0.001). There was neither any correlation between EEG latency and mRS (rho 0.087, p 0.236), nor with CPC (rho = 0.027, p = 0.603).
CONCLUSION
This analysis shows no correlation between delays of EEG recordings and mortality or functional outcomes at 6 months in critically ill adults.
SIGNIFICANCE
These findings might suggest that in critically ill adults mortality correlates with underlying brain injury rather than EEG delay.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology |
UniBE Contributor: |
Schindler, Kaspar Anton |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1872-8952 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
03 May 2022 10:40 |
Last Modified: |
05 Dec 2022 16:19 |
Publisher DOI: |
10.1016/j.clinph.2022.04.003 |
PubMed ID: |
35490437 |
Uncontrolled Keywords: |
Electroencephalography Intensive care unit Prognosis Seizures Status epilepticus |
BORIS DOI: |
10.48350/169706 |
URI: |
https://boris.unibe.ch/id/eprint/169706 |
Actions (login required)
 |
Edit item |