Michel, C; Lerch, Stefan; Büetiger, Jessica; Flückiger, Rahel; Cavelti, Marialuisa; Koenig, Julian; Kaess, Michael; Kindler, Jochen (2023). An ecological momentary assessment study of age effects on perceptive and non-perceptive clinical high-risk symptoms of psychosis. European child & adolescent psychiatry, 32(10), pp. 1841-1852. Springer 10.1007/s00787-022-02003-9
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Among individuals with clinical high risk for psychosis (CHR), perceptive symptoms are more frequent but have less clinical significance in children/adolescents compared to adults. However, findings are based on clinical interviews relying on patient's recall capacity. Ecological momentary assessment (EMA) can be used to explore experiences in real-time in the subject's daily life. The aim of this study was to assess frequency and stability of (perceptive and non-perceptive) CHR symptoms and to explore potential age effects. EMA was used in a sample of an early detection for psychosis service in Bern, Switzerland (N = 66; 11-36 years). CHR symptoms were recorded in random time intervals for seven days: eight assessments per day per subject, minimum time between prompts set at 25 min. CHR symptoms were additionally assessed with semi-structured interviews including the 'Structured Interview for Psychosis-Risk Syndromes' and the 'Schizophrenia Proneness Instruments'. Mixed-effects linear regression analysis on the frequency of CHR symptoms revealed a significant effect of age group, and the interaction CHR symptoms x age group for both perceptive and non-perceptive symptoms. Further, regarding stability of CHR symptoms, there was a significant effect of the interaction CHR symptoms x age group for perceptive symptoms only. Based on EMA, perceptive CHR symptoms were more frequently reported but less stable in children/adolescents compared with adults. Together with previous findings, our finding of higher instability/variability of perceptive symptoms in younger persons might suggest that with advancing age and more stability of CHR symptoms, clinical relevance (reduced psychosocial functioning) may increase.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Child and Adolescent Psychiatry and Psychotherapy 04 Faculty of Medicine > University Psychiatric Services > University Hospital of Child and Adolescent Psychiatry and Psychotherapy > Research Division |
UniBE Contributor: |
Michel, Chantal, Lerch, Stefan, Büetiger, Jessica, Flückiger, Rahel, Cavelti, Marialuisa (A), Koenig, Julian, Kaess, Michael, Kindler, Jochen |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1435-165X |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
20 May 2022 14:58 |
Last Modified: |
29 Sep 2023 00:11 |
Publisher DOI: |
10.1007/s00787-022-02003-9 |
PubMed ID: |
35585271 |
Uncontrolled Keywords: |
Basic symptoms EMA Experience sampling method Perceptive symptoms Psychosis risk |
BORIS DOI: |
10.48350/170136 |
URI: |
https://boris.unibe.ch/id/eprint/170136 |
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