Ebel, Sebastian; Kühn, Alexander; Aggarwal, Abhinav; Köhler, Benjamin; Behrendt, Benjamin; Gohmann, Robin; Riekena, Boris; Lücke, Christian; Ziegert, Juliane; Vogtmann, Charlotte; Preim, Bernhard; Kropf, Siegfried; Jung, Bernd; Denecke, Timm; Grothoff, Matthias; Gutberlet, Matthias (2022). Quantitative normal values of helical flow, flow jets and wall shear stress of healthy volunteers in the ascending aorta. European radiology, 32(12), pp. 8597-8607. Springer 10.1007/s00330-022-08866-5
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OBJECTIVES
4D flow MRI enables quantitative assessment of helical flow. We sought to generate normal values and elucidate changes of helical flow (duration, volume, length, velocities and rotational direction) and flow jet (displacement, flow angle) as well as wall shear stress (WSS).
METHODS
We assessed the temporal helical existence (THEX), maximum helical volume (HVmax), accumulated helical volume (HVacc), accumulated helical volume length (HVLacc), maximum forward velocity (maxVfor), maximum circumferential velocity (maxVcirc), rotational direction (RD) and maximum wall shear stress (WSS) as reported elsewhere using the software tool Bloodline in 86 healthy volunteers (46 females, mean age 41 ± 13 years).
RESULTS
WSS decreased by 42.1% and maxVfor by 55.7% across age. There was no link between age and gender regarding the other parameters.
CONCLUSION
This study provides age-dependent normal values regarding WSS and maxVfor and age- and gender-independent normal values regarding THEX, HVmax, HVacc, HVLacc, RD and maxVcirc.
KEY POINTS
• 4D flow provides numerous new parameters; therefore, normal values are mandatory. • Wall shear stress decreases over age. • Maximum helical forward velocity decreases over age.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology |
UniBE Contributor: |
Jung, Bernd |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1432-1084 |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
27 May 2022 07:28 |
Last Modified: |
05 Dec 2022 16:20 |
Publisher DOI: |
10.1007/s00330-022-08866-5 |
PubMed ID: |
35612663 |
Uncontrolled Keywords: |
4D flow Aortic flow Flow patterns Helical flow Magnetic resonance imaging |
BORIS DOI: |
10.48350/170272 |
URI: |
https://boris.unibe.ch/id/eprint/170272 |
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