Cardiac Phenotypes in Secondary Hypertension: JACC State-of-the-Art Review.

Januszewicz, Andrzej; Mulatero, Paolo; Dobrowolski, Piotr; Monticone, Silvia; Van der Niepen, Patricia; Sarafidis, Pantelis; Reincke, Martin; Rexhaj, Emrush; Eisenhofer, Graeme; Januszewicz, Magdalena; Kasiakogias, Alexandros; Kreutz, Reinhold; Lenders, Jacques W M; Muiesan, Maria Lorenza; Persu, Alexandre; Agabiti-Rosei, Enrico; Soria, Rodrigo; Śpiewak, Mateusz; Prejbisz, Aleksander and Messerli, Franz H (2022). Cardiac Phenotypes in Secondary Hypertension: JACC State-of-the-Art Review. Journal of the American College of Cardiology, 80(15), pp. 1480-1497. Elsevier 10.1016/j.jacc.2022.08.714

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Several forms of secondary hypertension carry a high risk of cardiac morbidity and mortality. Evaluation of cardiac phenotypes in secondary hypertension provides a unique opportunity to study underlying hormonal and biochemical mechanisms affecting the heart. We review the characteristics of cardiac dysfunction in different forms of secondary hypertension and clarify the mechanisms behind the higher prevalence of heart damage in these patients than in those with primary hypertension. Attention to the specific clinical/biochemical phenotypes of these conditions may assist clinicians to screen for and confirm secondary forms of hypertension. Thereby, early signs of heart damage can be recognized and monitored, allowing individualized treatment to delay or prevent evolution toward more advanced disease.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Kardiologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Kardiologie

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Rexhaj, Emrush, Soria Maldonado, Rodrigo, Messerli, Franz

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1558-3597

Publisher:

Elsevier

Language:

English

Submitter:

Pubmed Import

Date Deposited:

07 Oct 2022 09:20

Last Modified:

05 Dec 2022 16:26

Publisher DOI:

10.1016/j.jacc.2022.08.714

PubMed ID:

36202538

Uncontrolled Keywords:

cardiac damage cardiac events imaging secondary hypertension

BORIS DOI:

10.48350/173552

URI:

https://boris.unibe.ch/id/eprint/173552

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