Hachfeld, A; Atkinson, A; Stute, P; Calmy, A; Tarr, P E; Darling, K E A; Babouee Flury, B; Polli, C; Sultan-Beyer, L; Abela, I A; Aebi-Popp, K (2023). Does menopause transition influence viral suppression and adherence in Women living with HIV? Journal of acquired immune deficiency syndromes, 92(5), pp. 399-404. Wolters Kluwer Health 10.1097/QAI.0000000000003158
|
Text
Does_menopause_transition_influence_viral.177.pdf - Accepted Version Available under License Creative Commons: Attribution-Noncommercial-No Derivative Works (CC-BY-NC-ND). Download (368kB) | Preview |
BACKGROUND
Increasing numbers of women living with HIV transition through menopause. It is unclear if this transition has an impact on treatment adherence, viral suppression, psychiatric comorbidities or drug use. We aimed at examining adherence and viral suppression during the perimenopausal period and explored the influence of psychiatric comorbidities and active injection drug use (IDU).
SETTING
Retrospective Swiss HIV Cohort Study analysis from 01/2010 to 12/2018.
METHODS
We explored peri- and postmenopausal trends of viral blips, low-level viremia, viral failure, adherence, psychiatric comorbidities and IDU using interrupted time series (ITS) models.
RESULTS
Rates of depression and psychiatric care increased during perimenopause before decreasing afterwards. Negative treatment outcomes such as viral blips, low-level viremia, viral failure and low adherence steadily declined while transitioning through menopause - this was also true for subgroups of women with depression, psychiatric treatment and active IDU.
CONCLUSIONS
Increased rates of depression and psychiatric care while transitioning through menopause do not result in lower rates of adherence or viral suppression in women living with HIV in Switzerland.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology 04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Gynaecology |
UniBE Contributor: |
Hachfeld, Anna, Atkinson, Andrew David, Stute, Petra, Aebi-Popp, Karoline Lieselotte |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1944-7884 |
Publisher: |
Wolters Kluwer Health |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
11 Jan 2023 12:55 |
Last Modified: |
11 Mar 2023 00:14 |
Publisher DOI: |
10.1097/QAI.0000000000003158 |
PubMed ID: |
36595226 |
BORIS DOI: |
10.48350/176786 |
URI: |
https://boris.unibe.ch/id/eprint/176786 |
Actions (login required)
 |
Edit item |