Belibasakis, Georgios N; Belstrøm, Daniel; Eick, Sigrun; Gursoy, Ulvi K; Johansson, Anders; Könönen, Eija (2023). Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives. (In Press). Periodontology 2000 Wiley 10.1111/prd.12473
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Periodontology_2000_-_2023_-_Belibasakis_-_Periodontal_microbiology_and_microbial_etiology_of_periodontal_diseases_.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (1MB) | Preview |
This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis-centered interpretation. Reference is made to anerobic microbiology and to the discovery of select periodontal pathogens and their virulence factors, as well as to biofilms. The evolution of contemporary molecular methods and high-throughput platforms is highlighted in appreciating the breadth and depth of the periodontal microbiome. Finally clinical microbiology is brought into perspective with the contribution of different microbial species in periodontal diagnosis, the combination of microbial and host biomarkers for this purpose, and the use of antimicrobials in the treatment of the disease.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > School of Dental Medicine > Periodontics Research |
UniBE Contributor: |
Eick, Sigrun |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1600-0757 |
Publisher: |
Wiley |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
23 Jan 2023 12:27 |
Last Modified: |
24 Jan 2023 15:22 |
Publisher DOI: |
10.1111/prd.12473 |
PubMed ID: |
36661184 |
Uncontrolled Keywords: |
European anaerobic antibiotics antimicrobial biofilms clinical microbial diagnostics etiology host biomarkers pathogens periodontal microbiology |
BORIS DOI: |
10.48350/177718 |
URI: |
https://boris.unibe.ch/id/eprint/177718 |
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