Bauer, Andrea; Pesonen, Maria; Brans, Richard; Caroppo, Francesca; Dickel, Heinrich; Dugonik, Aleksandra; Larese Filon, Francesca; Geier, Johannes; Gimenez-Arnau, Ana M; Napolitano, Maddalena; Patruno, Cataldo; Rustemeyer, Thomas; Simon, Dagmar; Schuttelaar, Marie L A; Spiewak, Radoslaw; Stingeni, Luca; Vok, Marko; Weisshaar, Elke; Wilkinson, Mark; Valiukeviciene, Skaidra; ... (2023). Occupational contact allergy: The European perspective - analysis of patch test data from ESSCA between 2011-2020. Contact dermatitis, 88(4), pp. 263-274. Wiley-Blackwell 10.1111/cod.14280
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Contact_Dermatitis_-_2023_-_Bauer_-_Occupational_contact_allergy_The_European_perspective_analysis_of_patch_test_data.pdf - Accepted Version Available under License Publisher holds Copyright. Download (572kB) | Preview |
BACKGROUND
Occupational skin diseases have led the occupational disease statistics in Europe for many years. Especially occupational allergic contact dermatitis is associated with a poor prognosis and low healing rates leading to an enormous burden for the affected individual and for society.
OBJECTIVES
To present the sensitization frequencies to the most relevant allergens of the European baseline series in patients with occupational contact dermatitis (OCD) and to compare sensitization profiles of different occupations.
METHODS
The data of 16022 patients considered having OCD after patch testing within the ESSCA network between January 2011 and December 2020 were evaluated. Patients (n=46652) in whom an occupational causation was refuted served as comparison group.
RESULTS
The highest percentages of OCD were found among patients working in agriculture, fishery and related workers, metal industry, chemical industry, followed by building and construction industry, health care, food and service industry. Sensitizations to rubber chemicals (thiurams, carbamates, benzothiazoles) and epoxy resins were associated with at least a doubled risk of OCD. After a decline from 2014 onwards, the risks to acquire an occupation-related sensitization to methyl(chloro)isothiazolinone (MCI/MI) and especially to methylisothiazolinone (MI) seem to increase again. Sensitization rates to formaldehyde were stable, and to methyldibromo glutaronitrile (MDBGN) slightly decreasing over time.
CONCLUSIONS
Among allergens in the European Baseline Series, occupational relevance is most frequently attributed to rubber accelerators, epoxy resins and preservatives. This article is protected by copyright. All rights reserved.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology |
UniBE Contributor: |
Simon, Dagmar |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0105-1873 |
Publisher: |
Wiley-Blackwell |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
30 Jan 2023 13:43 |
Last Modified: |
25 Jan 2024 00:25 |
Publisher DOI: |
10.1111/cod.14280 |
PubMed ID: |
36694979 |
Uncontrolled Keywords: |
Baseline series RRID:SCR_001905 clinical epidemiology occupational contact allergy patch testing surveillance |
BORIS DOI: |
10.48350/177908 |
URI: |
https://boris.unibe.ch/id/eprint/177908 |
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