Goepfert, Christine; Gazdhar, Amiq; Frey, Felix J; Frey, Brigitte M (2011). Effect of electroporation-mediated diphtheria toxin A expression on PSA positive human prostate xenograft tumors in SCID mice. Prostate, 71(8), pp. 872-80. Hoboken, N.J.: Wiley-Blackwell 10.1002/pros.21303
Full text not available from this repository.Current therapies to treat prostate cancer are often limited. Since it has been shown that very low concentrations of diphtheria toxin A (DT-A) result in abrogation of protein synthesis and apoptosis of cells, DT-A might serve as an efficient killer in cancer gene therapy. For this purpose we investigated in a quantitative manner using a stereological approach the apoptotic effect of DT-A in androgen receptor (AR) and prostate specific antigen (PSA) expressing cells after tumor formation in both flanks of SCID mice.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Pneumology 04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Nephrology and Hypertension |
UniBE Contributor: |
Gazdhar, Amiq, Frey, Felix (B), Frey, Brigitte |
ISSN: |
0270-4137 |
Publisher: |
Wiley-Blackwell |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:11 |
Last Modified: |
29 Mar 2023 23:32 |
Publisher DOI: |
10.1002/pros.21303 |
PubMed ID: |
21456069 |
Web of Science ID: |
000289517500008 |
URI: |
https://boris.unibe.ch/id/eprint/1784 (FactScience: 203810) |
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