Benítez-Mateos, Ana I; Paradisi, Francesca (2023). Halomonas elongata: a microbial source of highly stable enzymes for applied biotechnology. Applied microbiology and biotechnology, 107(10), pp. 3183-3190. Springer 10.1007/s00253-023-12510-7
|
Text
CIRCRESAHA.123.321750.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (1MB) | Preview |
Extremophilic microorganisms, which are resistant to extreme levels of temperature, salinity, pH, etc., have become popular tools for biotechnological applications. Due to their availability and cost-efficacy, enzymes from extremophiles are getting the attention of researchers and industries in the field of biocatalysis to catalyze diverse chemical reactions in a selective and sustainable manner. In this mini-review, we discuss the advantages of Halomonas elongata as moderate halophilic bacteria to provide suitable enzymes for biotechnology. While enzymes from H. elongata are more resistant to the presence of salt compared to their mesophilic counterparts, they are also easier to produce in heterologous hosts compared with more extremophilic microorganisms. Herein, a set of different enzymes (hydrolases, transferases, and oxidoreductases) from H. elongata are showcased, highlighting their interesting properties as more efficient and sustainable biocatalysts. With this, we aim to improve the visibility of halotolerant enzymes and their uncommon properties to integrate biocatalysis in industrial set-ups. KEYPOINTS: • Production and use of halotolerant enzymes can be easier than strong halophilic ones. • Enzymes from halotolerant organisms are robust catalysts under harsh conditions. • Halomonas elongata has shown a broad enzyme toolbox with biotechnology applications.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP) |
UniBE Contributor: |
Benitez Mateos, Ana Isabel, Paradisi, Francesca |
Subjects: |
500 Science > 570 Life sciences; biology 500 Science > 540 Chemistry 000 Computer science, knowledge & systems |
ISSN: |
0175-7598 |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
14 Apr 2023 14:47 |
Last Modified: |
05 May 2023 00:16 |
Publisher DOI: |
10.1007/s00253-023-12510-7 |
PubMed ID: |
37052635 |
Uncontrolled Keywords: |
Biocatalysis Biotechnology Co-solvent stability Enzyme Halomonas Halotolerant |
BORIS DOI: |
10.48350/181702 |
URI: |
https://boris.unibe.ch/id/eprint/181702 |
Actions (login required)
 |
Edit item |