Improved Maximal Workload and Systolic Blood Pressure After Cardiac Rehabilitation Following Thoracic Aortic Repair: A SYSTEMATIC REVIEW AND META-ANALYSIS.

Koenders, Niek; van Zetten, Henrita; Smulders, Michelle; Verra, Martin; van Kimmenade, Roland R J; van Brakel, Thomas; Eijsvogels, Thijs M H; Smith, Tim (2023). Improved Maximal Workload and Systolic Blood Pressure After Cardiac Rehabilitation Following Thoracic Aortic Repair: A SYSTEMATIC REVIEW AND META-ANALYSIS. Journal of cardiopulmonary rehabilitation and prevention, 43(6), pp. 419-426. Lippincott Williams & Wilkins 10.1097/HCR.0000000000000798

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PURPOSE

It is of clinical importance to gain more knowledge about the risks and benefits of exercise in patients recovering from thoracic aortic repair. Therefore, the aim of this review was to perform a meta-analysis on changes in cardiorespiratory fitness, blood pressure, and the incidence of adverse events during cardiac rehabilitation (CR) in patients recovering from thoracic aortic repair.

REVIEW METHODS

We performed a systematic review and random-effects meta-analysis of outcomes before versus after outpatient CR in patients recovering from thoracic aortic repair. The study protocol was registered (PROSPERO CRD42022301204) and published. MEDLINE, EMBASE, and CINAHL were systematically searched for eligible studies. Overall certainty of evidence was scored with Grading of Recommendations Assessment, Development, and Evaluation (GRADE).

SUMMARY

We included five studies with data from in total 241 patients. Data from one study could not be used in our meta-analysis because they were provided in a different unit of measure. Four studies with data of 146 patients were included in the meta-analysis. The mean maximal workload increased with 28.7 W (95% CI: 21.8-35.6 W, n = 146, low certainty of evidence). The mean systolic blood pressure during exercise testing increased with 25.4 mm Hg (95% CI: 16.6-34.3, n = 133, low certainty of evidence). No exercise-induced adverse events were reported. These outcomes indicate that CR seems beneficial and safe to improve exercise tolerance in patients recovering from thoracic aortic repair, although outcomes were based on data from a small, heterogeneous group of patients.

Item Type:

Journal Article (Original Article)

Division/Institute:

?? DCD5A442C316E17DE0405C82790C4DE2 ??

UniBE Contributor:

Verra, Martin

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1932-7501

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Pubmed Import

Date Deposited:

24 May 2023 08:17

Last Modified:

28 Oct 2023 00:12

Publisher DOI:

10.1097/HCR.0000000000000798

PubMed ID:

37220027

URI:

https://boris.unibe.ch/id/eprint/182859

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