Imaging of Bioprosthetic Valve Dysfunction after Transcatheter Aortic Valve Implantation.

Alwan, Louhai; Bernhard, Benedikt; Brugger, Nicolas; De Marchi, Stefano F; Praz, Fabien Daniel; Windecker, Stephan; Pilgrim, Thomas; Gräni, Christoph (2023). Imaging of Bioprosthetic Valve Dysfunction after Transcatheter Aortic Valve Implantation. Diagnostics, 13(11) MDPI 10.3390/diagnostics13111908

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Transcatheter aortic valve implantation (TAVI) has become the standard of care in elderly high-risk patients with symptomatic severe aortic stenosis. Recently, TAVI has been increasingly performed in younger-, intermediate- and lower-risk populations, which underlines the need to investigate the long-term durability of bioprosthetic aortic valves. However, diagnosing bioprosthetic valve dysfunction after TAVI is challenging and only limited evidence-based criteria exist to guide therapy. Bioprosthetic valve dysfunction encompasses structural valve deterioration (SVD) resulting from degenerative changes in the valve structure and function, non-SVD resulting from intrinsic paravalvular regurgitation or patient-prosthesis mismatch, valve thrombosis, and infective endocarditis. Overlapping phenotypes, confluent pathologies, and their shared end-stage bioprosthetic valve failure complicate the differentiation of these entities. In this review, we focus on the contemporary and future roles, advantages, and limitations of imaging modalities such as echocardiography, cardiac computed tomography angiography, cardiac magnetic resonance imaging, and positron emission tomography to monitor the integrity of transcatheter heart valves.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Alwan, Louhai, Bernhard, Benedikt, Brugger, Nicolas Jacques, De Marchi, Stefano, Praz, Fabien Daniel, Windecker, Stephan, Pilgrim, Thomas, Gräni, Christoph

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2075-4418

Publisher:

MDPI

Language:

English

Submitter:

Pubmed Import

Date Deposited:

12 Jun 2023 11:21

Last Modified:

12 Jun 2023 11:30

Publisher DOI:

10.3390/diagnostics13111908

PubMed ID:

37296760

Uncontrolled Keywords:

TAVI bioprosthetic valve dysfunction bioprosthetic valve failure multimodality imaging structural valve deterioration

BORIS DOI:

10.48350/183311

URI:

https://boris.unibe.ch/id/eprint/183311

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