Kohler, Philipp; Babouee Flury, Baharak; Güsewell, Sabine; Egger, Thomas; Leal, Onicio; Brucher, Angela; Lemmenmeier, Eva; Meier Kleeb, Dorette; Möller, J Carsten; Ortner, Manuela; Rieder, Philip; Ruetti, Markus; Schmid, Hans-Ruedi; Stocker, Reto; Vuichard-Gysin, Danielle; Speer, Oliver; Wiggli, Benedikt; Besold, Ulrike; McGeer, Allison; Risch, Lorenz; ... (2023). Clinical symptoms of SARS-CoV-2 breakthrough infection during the Omicron period in relation to baseline immune status and booster vaccination-A prospective multicentre cohort of health professionals (SURPRISE study). Influenza and other respiratory viruses, 17(6), e13167. Wiley 10.1111/irv.13167
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Influenza_Resp_Viruses_-_2023_-_Kohler_-_Clinical_symptoms_of_SARS_CoV_2_breakthrough_infection_during_the_Omicron_period.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (650kB) | Preview |
The effects of different types of pre-existing immunity on the frequency of clinical symptoms caused by the SARS-CoV-2 breakthrough infection were prospectively assessed in healthcare workers during the Omicron period. Among 518 participants, hybrid immunity was associated with symptom reduction for dizziness, muscle or limb pain and headache as compared to vaccination only. Moreover, the frequencies of dizziness, cough and muscle or limb pain were lower in participants who had received a booster vaccine dose. Thus, hybrid immunity appeared to be superior in preventing specific symptoms during breakthrough infection compared to vaccination alone. A booster vaccine dose conferred additional symptom reduction.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Institute of Clinical Chemistry |
UniBE Contributor: |
Risch, Lorenz |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1750-2659 |
Publisher: |
Wiley |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
26 Jun 2023 16:47 |
Last Modified: |
16 Jul 2023 02:25 |
Publisher DOI: |
10.1111/irv.13167 |
PubMed ID: |
37346094 |
Uncontrolled Keywords: |
Covid‐19 breakthrough infection health professionals symptoms vaccine |
BORIS DOI: |
10.48350/184066 |
URI: |
https://boris.unibe.ch/id/eprint/184066 |
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