Heidemeyer, Kristine; Cazzaniga, Simone; Feldmeyer, Laurence; Imstepf, Valentina; Adatto, Maurice; Lehmann, Matthias; Rammlmair, Anna; Pelloni, Lorenzo; Jafari, S Morteza Seyed; Bossart, Simon (2023). Skin hyperpigmentation index in melasma: A complementary method to classic scoring systems. Journal of cosmetic dermatology, 22(12), pp. 3405-3412. Blackwell Science 10.1111/jocd.15866
|
Text
J_of_Cosmetic_Dermatology_-_2023_-_Heidemeyer_-_Skin_hyperpigmentation_index_in_melasma_A_complementary_method_to_classic.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (1MB) | Preview |
BACKGROUND
Due to relapsing nature of melasma with significant impact on quality of life, an objective measurement score is warranted, especially to follow-up the patients with melasma and their therapy response in a quantitative and precise manner.
AIMS
To prove concordance of skin hyperpigmentation index (SHI) with well-established scores in melasma and demonstrate its superiority regarding inter-rater reliability. Development of SHI mapping for its integration in common scores.
METHODS
Calculation of SHI and common melasma scores by five dermatologists. Inter-rater reliability was assessed by intraclass correlation coefficient (ICC) and concordance by Kendall correlation coefficient.
RESULTS
Strong concordance of SHI with melasma area and severity index (MASI)-Darkness (0.48; 95% CI: 0.32, 0.63), melasma severity index (MSI)-Pigmentation (0.45; 95% CI: 0.26, 0.61), and melasma severity scale (MSS) (0.6; 95% CI: 0.42, 0.74). Using step function for mapping SHI into pigmentation scores showed an improvement of inter-rater reliability with a difference in (ICC of 0.22 for MASI-Darkness and 0.19 for MSI-Pigmentation), leading to an excellent agreement.
CONCLUSION
Skin hyperpigmentation index could be an important additional cost-and time-conserving assessment method, to follow-up the patients with melasma undergoing brightening therapies in clinical studies, as well as in routine clinical practice. It is in strong concordance with well-established scores but superior regarding inter-rater reliability.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology |
UniBE Contributor: |
Heidemeyer, Kristine, Cazzaniga, Simone, Feldmeyer, Laurence, Imstepf, Valentina Anna, Adatto, Maurice Alfred, Rammlmair, Anna, Pelloni, Lorenzo Stefano, Jafari, Morteza, Bossart, Simon |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1473-2130 |
Publisher: |
Blackwell Science |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
27 Jun 2023 10:50 |
Last Modified: |
03 Dec 2023 00:12 |
Publisher DOI: |
10.1111/jocd.15866 |
PubMed ID: |
37349912 |
Uncontrolled Keywords: |
melasma score skin hyperpigmentation index |
BORIS DOI: |
10.48350/184086 |
URI: |
https://boris.unibe.ch/id/eprint/184086 |
Actions (login required)
 |
Edit item |