Lawsonia intracellularis proliferative enteropathy in a filly

Wuersch, K; Huessy, D; Koch, C.; Oevermann, A (2006). Lawsonia intracellularis proliferative enteropathy in a filly. Journal of veterinary medicine. Series A - physiology, pathology, clinical medicine, 53(1), pp. 17-21. Berlin: Blackwell 10.1111/j.1439-0442.2006.00776.x

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Proliferative enteropathy (PE) caused by the obligate intracellular bacterium Lawsonia intracellularis is a disease of high economic impact in swine worldwide. In most other species the disease occurs as a sporadic infection. This paper reports a PE caused by L. intracellularis in a 9-month-old Pura Raza Española filly with a history of profuse diarrhoea. Pathological lesions consisted of a severe proliferative enteritis associated with argyrophilic bacteria in the apical cytoplasm of proliferating crypt epithelium. Characteristic PCR products confirmed the presumptive diagnosis of L. intracellularis infection. To our knowledge this is the first report of PE in a horse in Europe caused by L. intracellularis.

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