Self-discharge during treatment for acute recreational drug toxicity: an observational study from emergency departments in seven European countries.

Vallersnes, Odd Martin; Dines, Alison M; Wood, David M; Heyerdahl, Fridtjof; Hovda, Knut Erik; Yates, Christopher; Giraudon, Isabelle; Caganova, Blazena; Ceschi, Alessandro; Galicia, Miguel; Liakoni, Evangelia; Liechti, Matthias E; Miró, Òscar; Noseda, Roberta; Persett, Per Sverre; Põld, Kristiina; Schmid, Yasmin; Scholz, Irene; Vigorita, Federico and Dargan, Paul I (2023). Self-discharge during treatment for acute recreational drug toxicity: an observational study from emergency departments in seven European countries. International journal of emergency medicine, 16(1), p. 86. BioMed Central 10.1186/s12245-023-00566-1

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BACKGROUND

Self-discharge is a risk factor for readmission and excess mortality. We assess the rate of self-discharge from the emergency department (ED) among presentations for acute recreational drug toxicity and identify factors associated with self-discharge.

METHODS

From the Euro-DEN Plus database of presentations to the ED with acute recreational drug toxicity, we extracted data from 11 centres in seven European countries from 2014 to 2017. Self-discharge was defined as taking one's own discharge or escaping from the ED before being medically cleared. We used multiple logistic regression analyses to look for factors associated with self-discharge.

RESULTS

Among 15,135 included presentations, 1807 (11.9%) self-discharged. Self-discharge rates varied from 1.7 to 17.1% between centres. Synthetic cannabinoids were associated with self-discharge, adjusted odds ratio 1.44 (95% confidence interval 1.10-1.89), as were heroin, 1.44 (1.26-1.64), agitation, 1.27 (1.10-1.46), and naloxone treatment, 1.27 (1.07-1.51), while sedation protected from self-discharge, 0.38 (0.30-0.48).

CONCLUSION

One in eight presentations self-discharged. There was a large variation in self-discharge rates across the participating centres, possibly partly reflecting different discharge procedures and practices. Measures to improve the management of agitation and cautious administration of naloxone to avoid opioid withdrawal symptoms may be approaches worth exploring to reduce self-discharge.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine

UniBE Contributor:

Liakoni, Evangelia, Scholz, Irene

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1865-1372

Publisher:

BioMed Central

Language:

English

Submitter:

Pubmed Import

Date Deposited:

30 Nov 2023 12:47

Last Modified:

03 Dec 2023 02:32

Publisher DOI:

10.1186/s12245-023-00566-1

PubMed ID:

38030969

Uncontrolled Keywords:

Discharge against medical advice Intoxication Leaving against medical advice Leaving without being seen Opioids Poisoning Recreational drug toxicity Self-discharge Substance use Substances of abuse

BORIS DOI:

10.48350/189648

URI:

https://boris.unibe.ch/id/eprint/189648

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