Stucki, Armin; Gerber, Peter; Acosta, Fernando; Cottagnoud, Marianne; Cottagnoud, Philippe (2006). Efficacy of telavancin against penicillin-resistant pneumococci and Staphylococcus aureus in a rabbit meningitis model and determination of kinetic parameters. Antimicrobial agents and chemotherapy, 50(2), pp. 770-3. Washington, D.C.: American Society for Microbiology 10.1128/AAC.50.2.770-773.2006
Full text not available from this repository. (Request a copy)The penetration of telavancin was 2% into inflamed meninges and ca. 1 per thousand into noninflamed meninges after two intravenous injections (30 mg/kg of body weight). In experimental meningitis, telavancin was significantly superior to vancomycin combined with ceftriaxone against a penicillin-resistant pneumococcal strain. Against a methicillin-sensitive staphylococcal strain, telavancin was slightly but not significantly superior to vancomycin.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
?? DCD5A442B9C7E17DE0405C82790C4DE2 ?? 04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Pneumology 04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology > Centre of Competence for Psychosomatic Medicine |
UniBE Contributor: |
Stucki, Andreas Hans, Gerber, Peter, Cottagnoud, Philippe |
ISSN: |
0066-4804 |
ISBN: |
16436742 |
Publisher: |
American Society for Microbiology |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:46 |
Last Modified: |
05 Dec 2022 14:14 |
Publisher DOI: |
10.1128/AAC.50.2.770-773.2006 |
PubMed ID: |
16436742 |
Web of Science ID: |
000235294200053 |
URI: |
https://boris.unibe.ch/id/eprint/19011 (FactScience: 1376) |
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