Schröder, Sebastian; Schulze Westhoff, Martin; Pfister, Tabea; Bleich, Stefan; Wedegärtner, Felix; Krüger, Tillmann Hc; Heck, Johannes; Groh, Adrian (2024). Characteristics of clinical-pharmacological recommendations in psychiatry. International journal of psychiatry in medicine, 59(3), pp. 393-405. Sage 10.1177/00912174231177230
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OBJECTIVE
Psychiatric patients in general, and elderly psychiatric patients in particular, are at risk of adverse drug reactions due to comorbidities and inappropriate polypharmacy. Interdisciplinary and clinical-pharmacologist-led medication reviews may contribute to medication safety in the field of psychiatry. In this study, we reported the frequency and characteristics of clinical-pharmacological recommendations in psychiatry, with a particular focus on geriatric psychiatry.
METHOD
A clinical pharmacologist, in collaboration with the attending psychiatrists and a consulting neurologist, conducted interdisciplinary medication reviews in a general psychiatric ward with a geropsychiatric focus at a university hospital over a 25-week period. All clinical and pharmacological recommendations were recorded and evaluated.
RESULTS
A total of 316 recommendations were made during 374 medication reviews. Indications/contraindications of drugs were the most frequently discussed topics (59/316; 18.7 %), followed by dose reductions (37/316; 11.7 %), and temporary or permanent discontinuation of medications (36/316; 11.4 %). The most frequent recommendations for dose reduction involvedbenzodiazepines (9/37; 24.3 %). An unclear or absent indication was the most common reason for recommending temporary or permanent discontinuation of the medication (6/36; 16.7 %).
CONCLUSION
Interdisciplinary clinical pharmacologist-led medication reviews represented a valuable contribution to medication management in psychiatric patients, particularly the elderly ones.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine |
UniBE Contributor: |
Pfister, Tabea |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1541-3527 |
Publisher: |
Sage |
Language: |
English |
Submitter: |
Rahel Fuhrer |
Date Deposited: |
08 Jan 2024 11:10 |
Last Modified: |
26 Apr 2024 00:13 |
Publisher DOI: |
10.1177/00912174231177230 |
PubMed ID: |
37194304 |
Uncontrolled Keywords: |
Clinical pharmacology drug safety geriatric psychiatry interdisciplinarity psychiatry |
BORIS DOI: |
10.48350/191309 |
URI: |
https://boris.unibe.ch/id/eprint/191309 |
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