Borys, Andryj M.; Kunzmann, Tim; Gil Negrete, Jose M.; Hevia, Eva (2023). Atom-efficient arylation of N-tosylimines mediated by cooperative ZnAr2/Zn(C6F5)2 combinations. Chemical communications, 59(49), pp. 7583-7586. Royal Society of Chemistry 10.1039/D3CC01490H
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By combining the Lewis acid Zn(C6F5)2 with nucleophilic diarylzinc (ZnAr2) reagents, we report the atom-efficient arylation of N-tosylimines under mild conditions. Mechanistic studies through the isolation of key intermediates reveal how the two zinc species act cooperatively to activate the imine substrate and regenerate the ZnAr2 reagent, enabling a limiting 50 mol% to be employed.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP) |
UniBE Contributor: |
Borys-Smith, Andryj Machaelo, Kunzmann, Tim Manuel, Gil Negrete Martin, Josep Maria, Hevia Freire, Eva |
Subjects: |
500 Science > 540 Chemistry |
ISSN: |
1359-7345 |
Publisher: |
Royal Society of Chemistry |
Language: |
English |
Submitter: |
Franziska Bornhauser-Rufer |
Date Deposited: |
18 Jan 2024 09:55 |
Last Modified: |
18 Jan 2024 10:56 |
Publisher DOI: |
10.1039/D3CC01490H |
BORIS DOI: |
10.48350/191735 |
URI: |
https://boris.unibe.ch/id/eprint/191735 |
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