Be aware of childhood stroke: Proceedings from EPNS Webinar.

Oesch, Gabriela; Münger, Robin; Steinlin, Maja (2024). Be aware of childhood stroke: Proceedings from EPNS Webinar. European journal of paediatric neurology, 49, pp. 82-94. Elsevier 10.1016/j.ejpn.2024.02.001

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Childhood arterial ischaemic stroke (AIS) is a significant health concern with increasing incidence. This review aims to provide an overview of the current understanding of childhood AIS. The incidence of childhood AIS is on the rise especially in developing countries, likely due to improved awareness and diagnostic capabilities. Aetiology of childhood AIS is multifactorial, with both modifiable risk factors and genetic predisposition playing important roles. Identifying and addressing these risk factors, such as infection, sickle cell disease, and congenital heart defects, is essential in prevention and management. Identifying underlying conditions through genetic testing is important for appropriate management and long-term prognosis. Clinically, distinguishing stroke from stroke mimics can be challenging. Awareness of important stroke mimics, including migraines, seizures, and metabolic disorders, is crucial to avoid misdiagnosis and ensure appropriate treatment. The diagnostic approach to childhood AIS involves a comprehensive "chain of care," including initial assessment, neuroimaging, and laboratory investigations. National guidelines play a pivotal role in standardizing and streamlining the diagnostic process, ensuring prompt and accurate management. Early intervention is critical in the management of childhood AIS. Due to the critical time window, the question if mechanical thrombectomy is feasible and beneficial should be addressed as fast as possible. Early initiation of antiplatelet or anticoagulation therapy and, in select cases, thrombolysis can help restore blood flow and minimize long-term neurological damage. Additionally, rehabilitation should start as soon as possible to optimize recovery and improve functional outcomes. In conclusion, childhood AIS is a growing concern. Understanding the increasing incidence, age distribution, risk factors, clinical presentation, diagnostic approach, and management strategies is crucial for optimized management of these patients.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine > Neuropaediatrics

Graduate School:

Graduate School for Health Sciences (GHS)

UniBE Contributor:

Oesch Nemeth, Gabriela, Münger, Robin, Steinlin, Maja

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1532-2130

Publisher:

Elsevier

Language:

English

Submitter:

Pubmed Import

Date Deposited:

11 Mar 2024 16:24

Last Modified:

03 May 2024 00:14

Publisher DOI:

10.1016/j.ejpn.2024.02.001

PubMed ID:

38447504

Uncontrolled Keywords:

Childhood stroke Clinics Incidence Risk factors Stroke Treatment

BORIS DOI:

10.48350/193928

URI:

https://boris.unibe.ch/id/eprint/193928

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