Successful kidney transplantation from donor with Marfan's syndrome

Farese, S; Vogt, B; Frey, F J; Huynh-Do, U (2006). Successful kidney transplantation from donor with Marfan's syndrome. American journal of transplantation, 6(8), pp. 1972-4. Oxford: Wiley-Blackwell 10.1111/j.1600-6413.2006.01389.x

Full text not available from this repository.

Marfan's syndrome is caused by mutations in the extracellular matrix protein fibrillin-1 with aortic aneurysm and dissection being its most life-threatening manifestations. Kidney transplantation from donors with Marfan's syndrome has never been reported in the literature, possibly because of reticences due to the underlying connective tissue disease. Here, we report two patients with end-stage renal disease, transplanted with the kidneys from a donor with Marfan's syndrome who died of aortic dissection and cerebral hemorrhage. After delayed graft function in both recipients, renal function normalized with no renovascular complications and negative proteinuria for 6 years in one patient and 2 years in the other patient, who died from an ischemic cerebrovascular insult. Kidneys from organ donors with Marfan's syndrome might be suitable for transplantation.

Item Type:	Journal Article (Further Contribution)
Division/Institute:	04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Nephrology and Hypertension
UniBE Contributor:	Farese, Stefan, Frey, Felix (B), Huynh-Do, Uyen
ISSN:	1600-6135
ISBN:	16889552
Publisher:	Wiley-Blackwell
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 14:47
Last Modified:	29 Mar 2023 23:32
Publisher DOI:	10.1111/j.1600-6413.2006.01389.x
PubMed ID:	16889552
Web of Science ID:	000238879700032
URI:	https://boris.unibe.ch/id/eprint/19775 (FactScience: 2718)