LeishGEM, Team (2024). LeishGEM: genome-wide deletion mutant fitness and protein localisations in Leishmania. Trends in parasitology, 40(8), pp. 675-678. Elsevier 10.1016/j.pt.2024.06.003
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LeishGEM is a genome-wide functional annotation community resource for Leishmania mexicana, where deletion mutant growth in vitro and in vivo is measured and protein localisation is determined by endogenous tagging and LOPIT-DC (localisation of organelle proteins by isotope tagging with differential centrifugation) spatial proteomics. Data are being made available pre-publication via http://leishgem.org which allows data-driven identification of the mechanisms for Leishmania parasitism.
Item Type: |
Journal Article (Further Contribution) |
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Division/Institute: |
08 Faculty of Science > Department of Biology > Institute of Cell Biology |
Subjects: |
500 Science > 570 Life sciences; biology |
ISSN: |
1471-5007 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
22 Jul 2024 14:09 |
Last Modified: |
10 Aug 2024 00:15 |
Publisher DOI: |
10.1016/j.pt.2024.06.003 |
PubMed ID: |
39030136 |
Additional Information: |
Sidonie Aellig, Ruth Etzensperger, Eva Gluenz, and Raquel Pereira are collaborators of the LeishGEM Team. |
Uncontrolled Keywords: |
LOPIT-DC Leishmania community resource gene deletion screen protein tagging |
BORIS DOI: |
10.48350/199113 |
URI: |
https://boris.unibe.ch/id/eprint/199113 |
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