Is the metabolic syndrome a new childhood disease?

Janner, M.; Mullis, P. E.; Flück, C. E. (2006). Is the metabolic syndrome a new childhood disease? Praxis - schweizerische Rundschau für Medizin, 95(13), pp. 493-500. Bern: Huber

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Overweight and obesity in children and adolescents have become a major public health problem in recent years throughout the world. The medical consequences of obesity may manifest as an increase in the prevalence of the metabolic syndrome in children and adolescents putting them at increased risk for future cardiovascular diseases. Obesity can cause insulin resistance and might disturb glucose homeostasis eventually leading to type 2 diabetes in susceptible patients. Insulin resistance is also involved in the pathogenesis of dyslipidemia in obese children characteristically presenting as hypertriglyceridemia and low HDL cholesterol. Even elevated blood pressure might be present in obese kids. Here we present a 12-year-old boy diagnosed with the metabolic syndrome. The diagnostic criteria of the metabolic syndrome in children and adolescents are discussed. Thoughts about pathophysiology and therapeutic options are offered.

Item Type:	Journal Article (Further Contribution)
Division/Institute:	04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine
UniBE Contributor:	Janner, Marco, Mullis, Primus-Eugen, Flück Pandey, Christa Emma
Subjects:	600 Technology > 610 Medicine & health
ISSN:	1661-8157
ISBN:	16602670
Publisher:	Huber
Language:	English
Submitter:	Anette van Dorland
Date Deposited:	04 Oct 2013 14:48
Last Modified:	02 Mar 2023 23:22
PubMed ID:	16602670
URI:	https://boris.unibe.ch/id/eprint/19992 (FactScience: 3071)