Ocular pulse amplitude in healthy subjects as measured by dynamic contour tonometry

Kaufmann, Claude; Bachmann, Lucas M; Robert, Yves C; Thiel, Michael A (2006). Ocular pulse amplitude in healthy subjects as measured by dynamic contour tonometry. Archives of ophthalmology, 124(8), 1104-8.. Chicago, Ill.: American Medical Association 10.1001/archopht.124.8.1104

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OBJECTIVES: To test whether dynamic contour tonometry yields ocular pulse amplitude (OPA) measurements that are independent of corneal thickness and curvature, and to assess variables of observer agreement. METHODS: In a multivariate cluster analysis on 223 eyes, the relationship between central corneal thickness, corneal curvature, axial length, anterior chamber depth, intraocular pressure, sex, age, and OPA measurements was assessed. Intraobserver and interobserver variabilities were calculated from repeated measurements obtained from 8 volunteers by 4 observers. RESULTS: The OPA readings were not affected by central corneal thickness (P = .08), corneal curvature (P = .47), anterior chamber depth (P = .80), age (P = .60), or sex (P = .73). There was a positive correlation between OPA and intraocular pressure (0.12 mm Hg/1 mm Hg of intraocular pressure; P<.001) and a negative correlation between OPA and axial length (0.27 mm Hg/1 mm of length; P<.001). Intraobserver and interobserver variabilities were 0.08 and 0.02 mm Hg, respectively, and the intraclass correlation coefficient was 0.89. CONCLUSIONS: The OPA readings obtained with dynamic contour tonometry in healthy subjects are not influenced by the structure of the anterior segment of the eye but are affected by intraocular pressure and axial length. We found a high amount of agreement within and between observers.

Item Type:	Journal Article (Original Article)
Division/Institute:	04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM)
UniBE Contributor:	Bachmann, Lucas
ISSN:	0003-9950
ISBN:	16908812
Publisher:	American Medical Association
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 14:48
Last Modified:	05 Dec 2022 14:15
Publisher DOI:	10.1001/archopht.124.8.1104
PubMed ID:	16908812
Web of Science ID:	000239758100003
URI:	https://boris.unibe.ch/id/eprint/20067 (FactScience: 3185)