Prospective study on bright lumen magnetic resonance colonography in comparison with conventional colonoscopy

Saar, B; Meining, A; Beer, A; Settles, M; Helmberger, H; Frimberger, E; Rummeny, E J; Rösch, T (2007). Prospective study on bright lumen magnetic resonance colonography in comparison with conventional colonoscopy. British journal of radiology, 80(952), pp. 235-41. London: British Institute of Radiology 10.1259/bjr/83959666

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The aim of this prospective trial was to evaluate sensitivity and specificity of bright lumen magnetic resonance colonography (MRC) in comparison with conventional colonoscopy (CC). A total of 120 consecutive patients with clinical indications for CC were prospectively examined using MRC (1.5 Tesla) which was then followed by CC. Prior to MRC, the cleansed colon was filled with a gadolinium-water solution. A 3D GRE sequence was performed with the patient in the prone and supine position, each acquired during one breathhold period. After division of the colon into five segments, interactive data analysis was carried out using three-dimensional post-processing, including a virtual intraluminal view. The results of CC served as a reference standard. In all patients MRC was performed successfully and no complications occurred. Image quality was diagnostic in 92% (574/620 colonic segments). On a per-patient basis, the results of MRC were as follows: sensitivity 84% (95% CI 71.7-92.3%), specificity 97% (95% CI 89.0-99.6%). Five flat adenomas and 6/16 small polyps (< or =5 mm) were not identified by MRC. MRC offers high sensitivity and excellent specificity rates in patients with clinical indications for CC. Improved MRC techniques are needed to detect small polyps and flat adenomas.

Item Type:	Journal Article (Original Article)
Division/Institute:	04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology
UniBE Contributor:	Saar, Bettina
ISSN:	0007-1285
ISBN:	17329681
Publisher:	British Institute of Radiology
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 14:51
Last Modified:	05 Dec 2022 14:15
Publisher DOI:	10.1259/bjr/83959666
PubMed ID:	17329681
Web of Science ID:	000247432700002
URI:	https://boris.unibe.ch/id/eprint/21554 (FactScience: 7411)