Feller, Martin; Huwiler, Karin; Stephan, Roger; Altpeter, Ekkehardt; Shang, Aijing; Furrer, Hansjakob; Pfyffer, Gaby E; Jemmi, Thomas; Baumgartner, Andreas; Egger, Matthias (2007). Mycobacterium avium subspecies paratuberculosis and Crohn's disease: a systematic review and meta-analysis. Lancet infectious diseases, 7(9), pp. 607-613. London: Elsevier 10.1016/S1473-3099(07)70211-6
![[img]](https://boris.unibe.ch/style/images/fileicons/text.png) |
Text
Feller LancetInfectDis 2007.pdf - Published Version Restricted to registered users only Available under License Publisher holds Copyright. Download (161kB) |
This systematic review assesses the evidence for an association between Mycobacterium avium subspecies paratuberculosis (MAP) and Crohn's disease. We analysed 28 case-control studies comparing MAP in patients with Crohn's disease with individuals free of inflammatory bowel disease (IBD) or patients with ulcerative colitis. Compared with individuals free of IBD, the pooled odds ratio (OR) from studies using PCR in tissue samples was 7.01 (95% CI 3.95-12.4) and was 1.72 (1.02-2.90) in studies using ELISA in serum. ORs were similar for comparisons with ulcerative colitis patients (PCR, 4.13 [1.57-10.9]; ELISA, 1.88 [1.26-2.81]). The association of MAP with Crohn's disease seems to be specific, but its role in the aetiology of Crohn's disease remains to be defined.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM) 04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology |
UniBE Contributor: |
Feller, Martin, Huwiler, Karin, Shang, Aijing, Furrer, Hansjakob, Egger, Matthias |
Subjects: |
600 Technology > 610 Medicine & health 300 Social sciences, sociology & anthropology > 360 Social problems & social services |
ISSN: |
1473-3099 |
ISBN: |
17714674 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:52 |
Last Modified: |
05 Dec 2022 14:16 |
Publisher DOI: |
10.1016/S1473-3099(07)70211-6 |
PubMed ID: |
17714674 |
Web of Science ID: |
000249091700018 |
BORIS DOI: |
10.7892/boris.22095 |
URI: |
https://boris.unibe.ch/id/eprint/22095 (FactScience: 30406) |
Actions (login required)
 |
Edit item |