Antiretroviral, Therapy in Low-Income Countries Collaboration of the Internation; Cohort Collaboration, ART; Brinkhof, MW; Egger, M; Boulle, A; May, M; Hosseinipour, M; Sprinz, E; Braitstein, P; Dabis, F; Reiss, P; Bangsberg, DR; Rickenbach, M; Miro, JM; Myer, L; Mocroft, A; Nash, D; Keiser, O; Pascoe, M; van der Borght, S; ... (2007). Tuberculosis after initiation of antiretroviral therapy in low-income and high-income countries. Clinical infectious diseases, 45(11), pp. 1518-21. Cary, N.C.: Oxford University Press 10.1086/522986
|
Text
45-11-1518.pdf - Published Version Available under License Publisher holds Copyright. Download (129kB) | Preview |
We examined the incidence of and risk factors for tuberculosis during the first year of highly active antiretroviral therapy in low-income (4540 patients) and high-income (22,217 patients) countries. Although incidence was much higher in low-income countries, the reduction in the incidence of tuberculosis associated with highly active antiretroviral therapy was similar: the rate ratio for months 7-12 versus months 1-3 was 0.48 (95% confidence interval, 0.36-0.64) in low-income countries and 0.36 (95% confidence interval, 0.26-0.50) in high-income countries. A low CD4 cell count at the start of therapy was the most important risk factor in both settings.
Item Type: |
Journal Article (Original Article) |
---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM) |
UniBE Contributor: |
Brinkhof, Martin, Egger, Matthias |
ISSN: |
1058-4838 |
ISBN: |
17990236 |
Publisher: |
Oxford University Press |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:52 |
Last Modified: |
05 Dec 2022 14:16 |
Publisher DOI: |
10.1086/522986 |
PubMed ID: |
17990236 |
Web of Science ID: |
000251080800020 |
BORIS DOI: |
10.48350/22112 |
URI: |
https://boris.unibe.ch/id/eprint/22112 (FactScience: 30456) |