[Bleeding complication due to accumulation of low-molecular-weight heparin in a patient with renal insufficiency]

Schneiter, S; Huynh-Do, U; Heizmann, M (2007). [Bleeding complication due to accumulation of low-molecular-weight heparin in a patient with renal insufficiency]. Praxis - schweizerische Rundschau für Medizin, 96(18), pp. 733-7. Bern: Huber

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We report of a 71-year-old woman with a history of chronic analgesic nephropathy, who underwent coronary angiography. Because of anterior ventricular aneurysm, anticoagulation with nadroparine was installed. Continued ACE-inhibitor and ASA with additional intravenous contrast substance lead to acute tubular necrosis with rapid decline of the renal function. Due to accumulation of the low molecular weight heparin, the patient developed an extensive retroperitoneal haematoma with circulatory shock and temporary anuric kidney failure. Low molecular weight heparins are commonly used during percutaneous coronary interventions. They are as safe and efficient compared to unfractioned heparin. But due to their renal elimination, they have to be monitored by measuring anti-factor Xa-activity if creatinine-clearance is <30 ml/min.

Item Type:	Journal Article (Further Contribution)
Division/Institute:	04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Nephrology and Hypertension
UniBE Contributor:	Huynh-Do, Uyen
ISSN:	1661-8157
ISBN:	17520842
Publisher:	Huber
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 14:54
Last Modified:	05 Dec 2022 14:16
PubMed ID:	17520842
URI:	https://boris.unibe.ch/id/eprint/23036 (FactScience: 38676)