Wyatt, Christopher C L; Maupome, Gerardo; Hujoel, Philippe P; MacEntee, Michael I; Persson, Gösta Rutger; Persson, Rigmor; Kiyak, H Asuman (2007). Chlorhexidine and preservation of sound tooth structure in older adults. A placebo-controlled trial. Caries research, 41(2), pp. 93-101. Basel: Karger 10.1159/000098041
|
Text
document.pdf - Published Version Available under License Publisher holds Copyright. Download (205kB) | Preview |
The Trial to Enhance Elderly Teeth Health (TEETH) was designed to test the impact of regular rinsing with a 0.12% chlorhexidine (CHX) solution on tooth loss, and the causes of tooth loss (caries, periodontal disease and trauma) were also investigated. This paper reports on the effectiveness of a 0.12% CHX solution for controlling caries using a tooth surface (coronal and root) survival analysis. A total of 1,101 low income elders in Seattle (United States) and Vancouver (Canada), aged 60-75 years, were recruited for a double-blind clinical trial and assigned to either a CHX (n = 550) or a placebo (n = 551) mouth rinse. Subjects alternated between daily rinsing for 1 month, followed by weekly rinsing for 5 months. All sound coronal and root surfaces at baseline were followed annually for up to 5 years. At each follow-up examination, those tooth surfaces with caries, restored, or extracted were scored as 'carious'. The hazard ratio associated with CHX for a sound surface to become filled, decayed, or extracted was 0.87 for coronal surfaces (95% confidence interval: 0.71-1.14, p = 0.20) and 0.91 for root surfaces (95% confidence interval: 0.73-1.14, p = 0.41). These findings suggest that regular rinsing with CHX does not have a substantial effect on the preservation of sound tooth structure in older adults.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > School of Dental Medicine > Department of Periodontology |
UniBE Contributor: |
Persson, Gösta Rutger, Persson, Rigmor |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0008-6568 |
Publisher: |
Karger |
Submitter: |
Eveline Carmen Schuler |
Date Deposited: |
04 Oct 2013 14:54 |
Last Modified: |
25 May 2023 11:50 |
Publisher DOI: |
10.1159/000098041 |
PubMed ID: |
17284909 |
Web of Science ID: |
000244107900002 |
BORIS DOI: |
10.7892/boris.23169 |
URI: |
https://boris.unibe.ch/id/eprint/23169 (FactScience: 40028) |
Actions (login required)
 |
Edit item |