Steinbach, William J; Cramer, Robert A; Perfect, B Zachary; Henn, Christina; Nielsen, Kirsten; Heitman, Joseph; Perfect, John R (2007). Calcineurin inhibition or mutation enhances cell wall inhibitors against Aspergillus fumigatus. Antimicrobial agents and chemotherapy, 51(8), pp. 2979-81. Washington, D.C.: American Society for Microbiology 10.1128/AAC.01394-06
Full text not available from this repository. (Request a copy)Calcineurin mutation or inhibition enhanced the antifungal morphological effect of cell wall inhibitors caspofungin or nikkomycin Z against Aspergillus fumigatus. Quantification of 1,3-beta-d-glucan revealed decreased amounts in the calcineurin A (DeltacnaA) mutant. Calcineurin can be an excellent adjunct therapeutic target in combination with other cell wall inhibitors against A. fumigatus.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine |
UniBE Contributor: |
Henn, Christina |
ISSN: |
0066-4804 |
ISBN: |
17502415 |
Publisher: |
American Society for Microbiology |
Language: |
English |
Submitter: |
Anette van Dorland |
Date Deposited: |
04 Oct 2013 14:55 |
Last Modified: |
05 Dec 2022 14:17 |
Publisher DOI: |
10.1128/AAC.01394-06 |
PubMed ID: |
17502415 |
Web of Science ID: |
000248523700043 |
URI: |
https://boris.unibe.ch/id/eprint/23560 (FactScience: 42418) |
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