Swoboda, Jessica R; Kiyak, H Asuman; Darveau, Richard; Persson, G Rutger (2008). Correlates of periodontal decline and biologic markers in older adults. Journal of periodontology, 79(10), pp. 1920-6. Chicago, Ill.: American Academy of Periodontology 10.1902/jop.2008.080005
Full text not available from this repository. (Request a copy)BACKGROUND: There is limited information on infectious and host responses distinguishing older people with or without active periodontitis. This study measured bacterial and serum cytokine and high-sensitivity C-reactive protein (hsCRP) levels in older persons. METHODS: Elders (mean age: 67 years), whose periodontal status had declined most or least (20% worst or 20% best) over 5 years, were enrolled. Two years later, they were classified as periodontally declining (active periodontitis [AP]), if they had at least five teeth with probing depth (PD) > or =5 mm, or stable (stable periodontally [SP]), if they did not. Groups were compared with respect to demographics, PD, clinical loss of attachment, subgingival bacteria, serum hsCRP, interleukin (IL)-1beta and -6, and chronic diseases. RESULTS: Ten AP and 24 SP subjects were identified; 13% of women and 44% of men from the original sample were in the AP group (P <0.05). Most Asians were SP; most whites and all African Americans were classified as having AP (P <0.01). More AP elders had osteoporosis (P <0.01), but the AP and SP groups did not differ with respect to IL-1beta and -6 or hsCRP. Bacterial counts were higher in the AP group for Parvimonas micra (previously Peptostreptococcus micros or Micromonas micros) (7.7 x 10(5) cells versus 3.8 x 10(5) cells; P <0.05), Prevotella intermedia (25.7 x 10(5) cells versus 9.8 x 10(5) cells; P <0.01), Tannerella forsythia (previously T. forsythensis) (16.2 x 10(5) cells versus 8.0 x 10(5) cells; P <0.05), and Streptococcus mutans (6.2 x 10(5) cells versus 2.0 x 10(5) cells; P <0.01). Three risk factors were most predictive of periodontal decline: PD, osteoporosis, and being white or African American. CONCLUSION: Periodontal decline was associated with osteoporosis, ethnicity, PD, gender, serum hsCRP, and levels of four bacterial species.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > School of Dental Medicine > Department of Periodontology |
UniBE Contributor: |
Persson, Gösta Rutger |
ISSN: |
0022-3492 |
Publisher: |
American Academy of Periodontology |
Language: |
English |
Submitter: |
Eveline Carmen Schuler |
Date Deposited: |
04 Oct 2013 15:02 |
Last Modified: |
05 Dec 2022 14:19 |
Publisher DOI: |
10.1902/jop.2008.080005 |
PubMed ID: |
18834247 |
Web of Science ID: |
000260142100013 |
URI: |
https://boris.unibe.ch/id/eprint/26841 (FactScience: 90031) |
Actions (login required)
 |
Edit item |