Evaluation of 15 mandibular reconstructions with Dumbach Titan Mesh-System and particulate cancellous bone and marrow harvested from bilateral posterior ilia

Iino, Mitsuyoshi; Fukuda, Masayuki; Nagai, Hirokazu; Hamada, Yoshiki; Yamada, Hiroyuki; Nakaoka, Kazutoshi; Mori, Yoshiyuki; Chikazu, Daichi; Saijo, Hideto; Seto, Ichiro; Ohkubo, Kazumi; Takato, Tsuyoshi (2009). Evaluation of 15 mandibular reconstructions with Dumbach Titan Mesh-System and particulate cancellous bone and marrow harvested from bilateral posterior ilia. Oral surgery, oral medicine, oral pathology, oral radiology and endodontology, 107(4), e1-8. Orlando, Fla.: Elsevier 10.1016/j.tripleo.2008.12.018

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This study reports on 15 mandibular reconstructions using the Dumbach Titan Mesh-System and particulate cancellous bone and marrow harvested from bilateral posterior ilia. All cases showed segmental defects. Eleven cases involved patients with malignant tumor. Six patients had received irradiation of 40-50 Gy. Reconstructions were performed immediately in 1 patient and secondarily in the remaining 14 patients. In 13 cases, mandibles were successfully reconstructed. Of these 13 patients, 9 reconstructions were completed without complications, whereas the other 4 cases showed complications. In 2 cases, reconstruction failed completely. Overall success rate was 87%. Statistical analysis revealed the extent of mandibular defect, but not malignancy of the original disease or radiotherapy of <or=50 Gy, as a significant factor in the occurrence of postoperative complications. Although no significant correlation was identified, cases in which mandibular continuity was lost at the time of reconstruction tended to show a higher postoperative complication rate. These results suggest that for the management of patients with malignant disease, resected mandible and soft tissue should be properly reconstructed using the metal plate and soft tissue flap at the time of cancer ablation surgery to reduce postreconstructive complications. Preoperative fabrication of the titanium mesh using a 3-dimensional skull model is expected to improve surgical outcomes.

Item Type:	Journal Article (Original Article)
Division/Institute:	04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Craniomaxillofacial Surgery
UniBE Contributor:	Seto, Ichiro
ISSN:	1079-2104
ISBN:	19201629
Publisher:	Elsevier
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 15:05
Last Modified:	05 Dec 2022 14:20
Publisher DOI:	10.1016/j.tripleo.2008.12.018
PubMed ID:	19201629
Web of Science ID:	000264559400031
URI:	https://boris.unibe.ch/id/eprint/28169 (FactScience: 118015)