Approach to the patient with drug allergy

Schnyder, Benno (2009). Approach to the patient with drug allergy. Immunology and allergy clinics of North America, 29(3), pp. 405-18. Philadelphia, Pa.: Elsevier 10.1016/j.iac.2009.04.005

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Drug allergies are adverse drug reactions mediated by the specific immune system. Despite characteristic signs (eg, skin rash) that raise awareness for possible drug allergies, they are great imitators of disease and may hide behind unexpected symptoms. No single standardized diagnostic test can confirm the immune-mediated mechanism or identify the causative drug; therefore, immune-mediated drug hypersensitivity reactions and their causative drugs must be recognized by the constellation of exposure, timing, and clinical features including the pattern of organ manifestation. Additional allergologic investigations (skin tests, in vitro tests, provocation tests) may provide help in identifying the possible eliciting drug.

Item Type:	Journal Article (Further Contribution)
Division/Institute:	04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Rheumatology and Immunology
UniBE Contributor:	Schnyder, Benno
ISSN:	0889-8561
Publisher:	Elsevier
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 15:11
Last Modified:	05 Dec 2022 14:22
Publisher DOI:	10.1016/j.iac.2009.04.005
PubMed ID:	19563988
Web of Science ID:	000268560300003
URI:	https://boris.unibe.ch/id/eprint/31432 (FactScience: 195943)