Regional lymph node staging in prostate cancer: prognostic and therapeutic implications

Burkhard, Fiona C; Studer, Urs E (2009). Regional lymph node staging in prostate cancer: prognostic and therapeutic implications. Surgical oncology, 18(3), pp. 213-8. Oxford: Elsevier 10.1016/j.suronc.2009.02.008

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The role of pelvic lymph node dissection (PLND) in prostate cancer, in which patients and to what extent it should be performed, remains a controversial topic. Preoperative diagnostic methods are more or less unreliable for lymph node staging and PLND remains the most reliable and accurate method. PLND is indicated in all patients with a PSA value >10 ng/ml and in those with a PSA <10 ng/ml if the Gleason score is > or = 7. If PLND is performed then it should always include the tissue along the external iliac vein, in the obturator fossa and on either side of the internal iliac vessels, up to where the ureter crosses the common iliac vessels. In conjunction with RRP extended PLND may increase staging accuracy, influence decision making with respect to adjuvant therapy and possibly impact outcome.

Item Type:	Journal Article (Further Contribution)
Division/Institute:	04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Urology
UniBE Contributor:	Studer, Urs
ISSN:	0960-7404
Publisher:	Elsevier
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 15:13
Last Modified:	05 Dec 2022 14:22
Publisher DOI:	10.1016/j.suronc.2009.02.008
PubMed ID:	19269808
Web of Science ID:	000270183700007
URI:	https://boris.unibe.ch/id/eprint/32208 (FactScience: 197189)