Intracranial Hemorrhage, Outcome, and Mortality After Intra-Arterial Therapy for Acute Ischemic Stroke in Patients Under Oral Anticoagulants

De Marchis, Gian Marco; Jung, Simon; Colucci, Giuseppe; Meier, Niklaus; Fischer, Urs; Weck, Anja; Mono, Marie-Luise; Galimanis, Aekaterini; Mattle, Heinrich P; Schroth, Gerhard; Gralla, Jan; Arnold, Marcel; Brekenfeld, Caspar (2011). Intracranial Hemorrhage, Outcome, and Mortality After Intra-Arterial Therapy for Acute Ischemic Stroke in Patients Under Oral Anticoagulants. Stroke, 42(11), pp. 3061-6. Baltimore, Md.: Lippincott Williams & Wilkins 10.1161/STROKEAHA.111.615476

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Use of intravenous tissue-type plasminogen activator (IV tPA) for acute ischemic stroke is restricted to patients with an international normalized ratio (INR) less than 1.7. However, a recent study showed increased risk of symptomatic intracranial hemorrhage after IV tPA use in patients with oral anticoagulants (OAC) even with an INR less than 1.7. The present study assessed the risk of symptomatic intracranial hemorrhage, clinical outcome, and mortality after intra-arterial therapy (IAT) in patients with and without previous use of OAC.

Item Type:	Journal Article (Original Article)
Division/Institute:	04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology 04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Haematology and Central Haematological Laboratory 04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology
UniBE Contributor:	De Marchis, Gian Marco, Colucci, Giuseppe, Meier, Niklaus, Fischer, Urs Martin, Weck, Anja, Mono, Marie-Luise, Galimanis, Aekaterini, Mattle, Heinrich, Schroth, Gerhard, Gralla, Jan, Arnold, Marcel, Brekenfeld, Caspar
Subjects:	600 Technology > 610 Medicine & health
ISSN:	0039-2499
Publisher:	Lippincott Williams & Wilkins
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 14:15
Last Modified:	02 Mar 2023 23:20
Publisher DOI:	10.1161/STROKEAHA.111.615476
PubMed ID:	21980194
Web of Science ID:	000296574500248
URI:	https://boris.unibe.ch/id/eprint/4022 (FactScience: 208131)